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Biosecurity of an animal facility requires constant vigilance on the part of Animal Care sand Research staff. Each vivarium has a designated traffic pattern. This traffic flow is based on the premise that clean areas should be entered before contaminated areas, in a progressive fashion. Clean supplies should be gathered before entering any animal room. Once an animal room has been entered, research personnel should not enter the clean side of the cagewasher. Additionally, research personnel should avoid entering the dirty side of the cagewasher at any time. Arrangements can be made with the vivarium Area Leader for clean supplies to be prepared in advance. It is especially important to properly use disinfectant foot baths, spray the soles of shoes, or don shoe covers prior to entering any animal rooms. This will reduce the potential for personnel to introduce pathogens into the animal holding rooms.